icer semaglutide white paper affordable access to glp-1 obesity medications 2025 Payers Consider Policy Options for Access to GLP-1 Obesity Medications Tirzepatide found to be more

Tirzepatide (Mounjaro, Zepbound) Strengths: Highest efficacy for both glucose control and weight loss Dual mechanism (GLP-1 + GIP) may provide unique benefits Once-weekly dosing Generally well-tolerated Considerations: Higher cost than semaglutide Less long-term safety data (newer medication) Cardiovascular outcome trial not yet complete (though expected to be positive) Best for: Patients prioritizing maximum weight loss

It helps the body produce and replenish white blood cells, particularly lymphocytes, which produce antibodies to fight infections

For a 200-pound woman, this translates to 10-30 pounds of loss

Adding Farxiga further helped manage her blood sugar

This is naturally produced in the body and stimulates melanogenesis, also known as the alpha-melanocyte-stimulating hormone

Chinese Medical Journal 2017, 130: 767-775